Conference - Rapid and affordable testing of AMR
23-25 November 2022
We are excited to invite you to a conference on the future of rapid testing of antimicrobial resistance.
The focus points of the conference:
- The AMR DetecTool project – Facing the challenges of AMR
- Low and middle-income countries and rapid AMR testing
- The techniques and future of the lateral flow immunoassay
This conference is the closing event of the AMR DetecTool project (2020-2022) funded by the European Institution of Innovation and Technology – Health. To learn more about this project, please visit the project website and the Knowledge Portal.
This conference will be a hybrid event: we invite the research community and every interested expert to participate face-to-face (up to 120 participants), while the event will be also available online.
Language of the event: English
Both the in-person and the online participation at this event is free of charge.
REGISTER FOR THE EVENT – CLICK HERE
Date And Time
23 Nov 2022 @ 13:30 to 18:00 – only for project partners
24 Nov 2022 @ 9:00 to 19:30
25 Nov 2022 @ 9:00 to 14:00
Registration end date
23 Nov 2022
Location
Paris
13:30 – 14:00 | Registration/Coffee |
14:00 – 14:15 | Welcome by Hervé Volland, Project Coordinator, CEA |
14:15 – 14:30 | Overview of the AMR DetecTool project – Open project issues concerning reporting and financing Speaker: Jordi Vila Barcelona Institute for Global Health, IS Global |
14:30 – 14:45 | The AMR rapid test device production Speaker: Hervé Volland |
14:45 – 15:15 | Testing the device and optimising the protocol in hospitals – WP3 results Speaker: Thierry Naas Assistance Publique Hôpitaux de Paris, APHP |
15:15 – 15:45 | Refreshments & stretching break |
15: 45 – 16:30 | Experiences learnt during the project – Interactive group session Session animator: Zoltan Albert Aszalos Chief project manager, Semmelweis University, Health Services Management Training Centre |
16:30 – 17:00 | Plenary feedback Feedback from group session and evaluation of success/main issues/next improvements |
17:00 – 18:00 | Moving ahead with the AMR DetecTool consortium Discussion on future project calls and funding opportunities, Horizon Europe and EIT Health calls EIT Health Flagship #3: Tackling the advanced therapies and MedTech market failures in Europe, fight against the AntiMicrobial Resistance challenge |
END of Consortium Meeting |
Agenda of the conference
CONFERENCE DAY 1 - 24th November 2022 | |
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9:00 - 9:20 | Registration/Refreshments |
Morning session | Focus 1: The AMR DetecTool project - Facing the challenges of AMR |
9:20 - 9:30 | Welcome by Hervé Volland, Project Coordinator Research Engineer, CEA |
9:30 - 10:00 | Keynote lecture 1: Mandatory notification system in France: a lesson to follow? Speaker: Bruno Coignard Director of Infectious Diseases at Public Health France |
10:00 - 10:30 | Keynote lecture 2: AMR and emerging resistance threats around the world, what is coming next, are we prepared? Speaker: Gian Maria Rossolini Professor of Microbiology and Clinical Microbiology University of Florence Director of the Clinical Microbiology Unit Florence Careggi University Hospital |
10:30 - 11:00 | Refreshments break |
11:00 - 11:30 | Clinical testing of the AMR DetecTool device in real-life conditions Testing CTXM; Carba 5; Oxa 23 and 3GC Speaker: Mariana Fernandez Clinical microbiologist, Hospital Clinic of Barcelona |
11:30 - 12:00 | Evaluating the advantages of the AMR DetecTool device Main results WP5 Speaker: Thierry Naas Associate Professor in Medical Microbiology and Head of the INSERM Team at CEA |
12:00 - 12:25 | Demonstrating the cost-saving impact of the device with health economics research Main results WP7 Speaker: Magda Rosenmöller Associate Professor and Academic Director of IESE CRHIM |
12:25 - 13:00 | Sharing information on the AMR DetecTool project WP6/8 Speaker: Albert Zoltan Aszalos Chief project manager, Semmelweis University, Health Services Management Training Centre |
13:00 - 14:00 | Lunch |
Afternoon session | Focus 2: Low and middle-income countries and rapid AMR testing |
14:00 - 15:30 | Keynote lecture series 3: AMR in LMIC 14:00 - 14:30 Minilab project of Médecins Sans Frontières Speaker: Jean-Baptiste Ronat Chief Executive Officer and AMR Lab specialist of IQLS 14:30 - 15:00 WHO, Global Antimicrobial Resistance and Use Surveillance System (GLASS) 15:00 - 15:30 Specific needs and current workflows in LMIC: examples from Togo, Mozambique and Morocco. Speakers: Sika Dossim Head of the Foundational and Biological Sciences Department, University of Kara Inacio Mandomando Coordinating Researcher, Mahinça Health Research Centre Houssain Tligui Head of the Research Laboratory, Centre Hospitalier Ibn Sina |
15:30 - 16:00 | Refreshments break |
16:00 - 17:00 | The usefulness of LFIA, AMR Detectool in LMIC Small group discussions on how, where and when to use it, what are the exact needs, and how could we respond to these needs |
17:00 - 18:00 | Restitution of discussions |
18:00 - 19:30 | Networking Apéritif |
CONFERENCE DAY 2 - 25TH NOVEMBER 2022 | |
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9:00 - 9:30 | Registration/Coffee |
Morning session | Focus 3: The techniques and future of the lateral flow immunoassay |
9:30 - 10:00 | Keynote lecture 4: Future of Rapid diagnostics in AMR Ultra-fast PCR, WGS, Rapid AST, microfluidics, and the place of LFIA Speaker: Thierry Naas Head of the INSERM Team, CEA |
10:00 - 11:00 | Keynote lecture series 5: Future development of LFIA for AMR 10:00 - 10:20 LFIA to combine enzymatic activity and enzyme detection Speaker: Christian Moguet Doctoral researcher, CEA 10:20 - 10:40 LFIA to reveal LAMP products Speaker: Lilas Pommies Doctoral researcher, CEA 10:40 - 11:00 The pipeline of new products: LFIA and clipsable Detectool Speaker: Lucie Baujard-Lamotte R&D Director in Biochemistry and Process Optimisation, NG Biotech |
11:00 - 11:20 | Refreshments break |
11:20 - 12:00 | Roundtable discussion The AMR DetecTool Other clinical unmet needs that can/should be addressed by LFIA (general discussion) - fungi, CRP, lactate, PCT, and others? |
12:00 - 12:30 | Closing the AMR DetecTool project: thank you, goodbye and see you again Speakers: H. Volland and a representative of EIT Health |
12:30 - 14:00 | Lunch |
END of conference |
Speakers
Albert Zoltan Aszalos
Senior Project Manager, Semmelweis University
Aszalos has over 10 years of experience in leading international healthcare projects funded by the European Union, the European Institute of Innovation and Technology, and the World Health Organisation. He holds an MA in Economics, an MPhil in Law, an Executive MBA and an MSc in Business Analytics both accredited by New York State’s Department of Education, and is currently undertaking an MSc in Health Management.
Lucie Baujard-Lamotte
R&D Director in Biochemistry and Process Optimisation, NG Biotech
Dr Baujard-Lamotte has over 15 years of high level research experience, predominately in industry. She has led a number of industrial projects including those related to haemostasis diagnosis and the production of immune-reactive supports by protein deposition. She holds a PhD in Molecular Biochemistry and Biology and an MSc in Organised Matter and Living Systems, both undertaken at CY Cergy Paris Université.
Bruno Coignard
Director of Infectious Diseases at Santé Publique France (Public Health France)
Dr Coignard MD, MSc is a medical epidemiologist specialised in the epidemiology of healthcare-associated infections (HAI) and antimicrobial resistance (AMR). He previously trained as an Epidemic Intelligence Officer (EIS) at the Centers for Disease Control and Prevention (CDC), Hospital Infections Program. His areas of work include the development, implementation and assessment of surveillance systems; early warning and outbreak investigation; management of collaborative surveillance programs; linkage with multiple partners at regional, national, European and international level; and scientific expertise in relevant national and European bodies.
Sika Dossim
Head of the Foundational and Biological Sciences Department, University of Kara
Dr Dossim holds a PhD in Pharmacy, Health and Well-Being from the Cheikh Anta Diop University of Dakar, Senegal. She is Head of the Foundational and Biological Sciences Department at the University of Kara, Togo. Dr Dossim has co-authored a number of publications on topics including Lassa virus, rapid testing related to tuberculosis, and the prevalence of hepatitis B and HIV in chronic haemodialysis patients.
Mariana Fernandez
Clinical microbiologist, Hospital Clinic of Barcelona
Dr Fernandez is a graduate of medicine and has worked as a clinical microbiologist since 2020. She has been a member of virology staff at the Hospital Clinic of Barcelona in the area of COVID-19 since May 2020. Currently, she is working in the blood culture section and Department of Mycobacteria as part of her PhD research in non-tuberculous mycobacteria infection.
Inacio Mandomando
Coordinating Researcher, Mahinça Health Research Centre
Dr Mandomando holds a Bachelor’s degree in Veterinary Medicine and a PhD in Microbiology from the Universitat de Barcelona. He has undertaken further studies in Molecular Biology at the University of Maryland School of Medicine. He currently works as Coordinating Researcher at the Mahinça Health Research Centre in Mahinça, Mozambique and has co-authored over fifteen publications.
Christian Moguet
Doctoral researcher, CEA
Moguet holds degrees in Biology and Biological Engineering. He is currently undertaking a PhD in Biotechnology at Université Paris-Sanclay, funded by CEA. Moguet is part of the AMR team at CEA led by Dr Hervé Volland and works on the development of rapid tests for the detection of bêta-lactamases.
Thierry Naas
Head of the INSERM Team, CEA
Dr Naas is an Associate Professor in Medical Microbiology and Head of the INSERM Team at CEA. He has access to clinically-relevant pathogens through his hospital duties and to a unique collection of >30,000 MDR Gram-negatives (as the director of the French-NRC for AMR). This team has expertise in microbiology, genomics, structure-function relationships, diagnostics development and small molecule screening for antimicrobial activity.
Lilas Pommies
Doctoral researcher, CEA
Pommies is currently a PhD student at the CEA Paris-Saclay, having attended an engineering school. She is part of the AMR team at CEA led by Dr Hervé Volland, and is currently working on the sample preparation for the detection of bacteria with loop-mediated isothermal amplification (LAMP) and mass spectrometry (MALDI).
Jean-Baptiste Ronat
Chief Executive Officer and AMR Lab specialist of IQLS
Ronat graduated in biology and biotechnology laboratory analysis at Lyon University. After working for 10 years auditing and implementing laboratory capacity strengthening projects in various fields of biological diagnosis in low- and middle-income countries for Médecins Sans Frontieres (MSF) and the World Health Organization, he developed a particular interest in clinical bacteriology. He obtained an MPH in infectious risk management with a specialty of clinical bacteriology at Pasteur Institute School, France with a thesis on a retrospective study on antibiotic resistance of bacteria responsible for osteoarticular infections in victims of the Iraqi conflict. In 2021, after joining Paris MSF Headquarters to work on ways to improve access to diagnosis and monitoring of microbial infections and antimicrobial resistance. Currently he is the Chief Executive Officer and AMR Lab specialist of IQLS (Integrated Quality Laboratory Services).
Magda Rosenmöller
Associate Professor and Academic Director of IESE CRHIM
Dr Rosenmöller is Associate Professor at IESE Business School, and Academic Director of IESE CRHIM (Centre for Research in Health Innovation Management). She holds a PhD in Health Policy (University of London), a medical degree from University Louis Pasteur, Strasbourg, France, as well as an MBA from IESE (Barcelona, Spain). Her areas of interest include health management, managing innovation and entrepreneurship in health care & education, the Digital Transformation / AI in HealthCare and global health. She served as a senior expert at the World Bank LAC Region (2001-2) and in different assignments for the European Commission (health research and policy), the European Parliament and the ECDC, such as rapporteur on the Role of Universities in Regional Development (2013) and the first interim evaluation of the Innovative Medicine Initiative (IMI). She holds a leading role in EIT Health (since 2015) particularly in the Public Affairs Group and CAMPUS activities.
Gian Maria Rossolini
Professor of Microbiology and Clinical Microbiology University of Florence
Director of the Clinical Microbiology Unit Florence Careggi University Hospital
Houssain Tligui
Head of the Research Laboratory, Centre Hospitalier Ibn Sina
Dr Tligui, MD is Professor of Parasitology and Medical Mycology and Head of the Research Laboratory at the Centre Hospitalier Ibn Sina in Rabat, Morocco. He currently teaches at the Faculty of Medicine and Pharmacy of Rabat and is a member of a number of professional societies including the French Societies of Parasitology and Mycology and the International Society of Clinical Biology.
Volland, Hervé
Research Engineer, CEA
Hervé Volland, PhD, has worked for the French Alternative Energies and Atomic Energy Commission (CEA) since 2001 in the development and validation of immunoassays. He works on the development and optimisation of rapid tests (lateral flow immunoassays) for environmental detection or diagnosis and has coordinated European projects funded by EIT Health. Dr Volland has developed several lateral flow immunoassays for the detection of toxins and pathogens in the bioterrorism domain. Three tests resulting from this research (Carba5; CTX-M-M and MCR1) are now marketed in more than 50 countries. Since 2015 he has supervised the development of tests for antimicrobial resistance detection. He has authored/co-authored sixty peer-reviewed publications and filed seven patents.